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Agni casti fructus Keuschlammfrüchte
Published May 15, 1985; Replaced
December 2, 1992
Name of Drug
Agni casti fructus; chaste tree fruit, vitex fruit.
Composition of Drug
Chaste tree fruit composed of the ripe, dried fruits of
Vitex agnus castus L. [Fam.Verbenaceae], as well as their
preparations in effective dosage.
Pharmacological Properties,
Pharmacokinetics, Toxicology
There is evidence that aqueous-alcoholic extracts of chaste
tree fruit inhibit secretion of prolactin in vitro. In human
pharmacology there are no data about the lowering of prolactin
levels. There is no knowledge regarding pharmacokinetics.
Systematic studies about toxicology are unknown.
Clinical Data
1. Uses
Irregularities of the menstrual cycle. Premenstrual complaints.
Mastodynia. Note: In case of feeling of tension and swelling
of the breasts and at disturbances of menstruation, a physician
should be consulted for diagnosis.
2. Contraindications
None known.
3. Side Effects
Occasional occurrence of itching, urticarial exanthemas.
4. Special Cautions for
Use
None known.
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